Because of generous benefactors, your present these days can have 5X the effects to advance AI innovation at Mayo Clinic.Watch Carefully (one)mitotane decreases amounts of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Mitotane is a solid inducer of cytochrome P-4503A4; watch when coadministered with CYP3A